Endocrine Abstracts

Growth hormone (GH) raises serum levels of insulin-like growth factor (IGF)-I, which is mitogenic and antiapoptotic. There is evidence that raised endogenous levels of GH and IGF-I might be associated with increased risk of certain solid cancers, but there have been no data on long-term risks of solid cancers after GH treatment.A cohort study was undertaken of cancer incidence and mortality in a cohort of 1848 patients in the UK who were treated in childhood and early adul...